ExciIQ's origin story

It isn't always the medicine. Sometimes it's what's in it.

In May 2026, my wife had three emergencies and spent six days in intensive care on an epinephrine drip. The first came on her fifth day taking a new H2 blocker. The third came on her third day in intensive care, after she was given a generic antihistamine. At her bedside, I started reading the inactive ingredients of both medications on my phone. That work became ExciIQ.

Illustration
GENERIC H2 BLOCKER · YELLOW TABLETIllustration, with no imprint. Her actual tablet was an H2 blocker, a medicine that reduces stomach acid. Its yellow came from two iron oxide color additives listed among its inactive ingredients.

Before

A routine step before surgery

My wife was getting ready for dental surgery. Beforehand, an H2 blocker was added to her medicines.

For three days she took it without trouble. Like most people, we assumed any problem from a pill would come from the drug itself.

What happened

A new tablet, then six days in intensive care

  1. Days 1 to 3She takes the new tablet each night. No symptoms.
  2. Day 4 · eveningA little flushing around her mouth.
  3. Day 5 · 45 minutes after her doseAnaphylaxis. She gives herself two epinephrine injections. The emergency squad takes her to the hospital.
  4. Two days laterShe comes home from the hospital, no longer taking the H2 blocker.
  5. Back homeAnaphylaxis again. She is admitted to intensive care on an epinephrine drip. She stays six days.
  6. Intensive care · day 3She is given a generic antihistamine tablet. Then, even with epinephrine running, she has anaphylaxis again.
  7. At her bedsideI start reading labels on my phone. I want to know what the H2 blocker and the antihistamine have in common. That question later became Friend or Foe, a workup for clinicians.

My wife and I talked about this on The POTScast, Episode 324: When “Inactive” Ingredients Aren’t: The ICU stay that inspired ExciIQ, with Nicole & Jeff Allen and Mike Brook (Standing Up to POTS, 2026-08-23).

The labels

Two labels, the same color additives

Illustration
Medicine 1 · the H2 blockerIllustration

GENERIC H2 BLOCKER TABLET

Film-coated · yellow · added before dental surgery

  • H2 BLOCKERActive ingredient
  • Inactive ingredients
  • MICROCRYSTALLINE CELLULOSEOn both labels
  • STARCH, CORN
  • MAGNESIUM STEARATE
  • HYPROMELLOSE
  • FERRIC OXIDE REDOn both labels
  • FERRIC OXIDE YELLOWOn both labels
Medicine 2 · the antihistamineIllustration

GENERIC ANTIHISTAMINE TABLET

Given in intensive care on day 3

  • ANTIHISTAMINEActive ingredient
  • Inactive ingredients
  • CROSCARMELLOSE SODIUM
  • MICROCRYSTALLINE CELLULOSEOn both labels
  • POVIDONE
  • POLYETHYLENE GLYCOL
  • FERRIC OXIDE REDOn both labels
  • FERRIC OXIDE YELLOWOn both labels

Illustration. Example labels for this story, not the actual products.

On both labels

Ferric oxide red and ferric oxide yellow. The two medicines had different active ingredients. Both of her actual medicines listed the same two iron oxide color additives.

The story most of us tell ourselves

"I must be allergic to that drug."

When a reaction follows a new medicine, that's the natural conclusion. People then avoid that medicine, and sometimes others like it.

But one drug comes in many versions. Each manufacturer chooses its own inactive ingredients. Sometimes the active ingredient isn't the problem at all.

Her story involves two color additives. Researchers have studied many other inactive ingredients. One 2019 study tracked 38 that are reported to cause allergic symptoms. Iron oxides were not among them.

92.8%

of 42,052 oral solid dosage forms studied contained at least one of 38 inactive ingredients reported to cause allergic symptoms after oral exposure.

Reker et al., Science Translational Medicine, 2019

Most people don't react to inactive ingredients. For the people who do, the details on the label matter.

What changed

Her care team's working explanation, and her decision

Before

We assumed she was allergic to the H2 blocker.

After

Her care team's working explanation was the iron oxide color additives.

My wife decided, with her care team, to avoid all color additives in her medicines, iron oxides included. That decision is hers.

ExciIQ played no part in it. ExciIQ did not exist yet.

Why I built it

Clinicians should see this before a crisis

ExciIQ didn't exist before May 2026. I've spent more than 25 years curating data solutions and building enterprise-class applications. For more than 7 of those years, I worked closely with pharmacy and medical claims data. Even so, I had to piece this together by hand, on a phone, in a hospital room.

That shouldn't be how anyone learns what a label lists. The clinicians caring for patients like my wife should be able to see it first, long before a crisis.

So I built ExciIQ. ExciIQ makes the inactive ingredients in every FDA-labeled human medication visible, comparable, and searchable. It is built for licensed physicians, nurse practitioners, physician assistants, pharmacists, and registered dietitians.

Professional use only — not for patient diagnosis or treatment decisions.

For licensed, certified, or registered healthcare professionals. Supports — does not replace — professional judgment. Not for time-critical use. Review the basis and current FDA label.

Jeff Allen, founder of ExciIQ · Ohio

Where to go from here

If this sounds familiar

For healthcare professionals

ExciIQ

ExciIQ shows what each medication's FDA label lists, including the inactive ingredients, and lets you compare products side by side. It is built for licensed physicians, nurse practitioners, physician assistants, pharmacists, and registered dietitians.

Join the pilot

Professional use only — not for patient diagnosis or treatment decisions.

For licensed, certified, or registered healthcare professionals. Supports — does not replace — professional judgment. Not for time-critical use. Review the basis and current FDA label.

For patients and families

WhatsInYourMeds

WhatsInYourMeds shows you the ingredients your medication's FDA label lists. That includes the "inactive" ingredients, called excipients.

For a provider who doesn’t use ExciIQ, you can download a PDF of your list and give it to them.

In private preview. Invitation-only for now.

Visit WhatsInYourMeds

WhatsInYourMeds shows what the labels of your medicines and supplements list, and lets you share that list with your care team. It does not diagnose, recommend, or tell you whether a medicine or supplement is right for you.

For information and education only — not medical advice. Never stop, start, or change a medication without talking to your prescriber.